Non-vivo approach complements microsampling and lean sample analysis
The importance of minimizing animal use was highlighted in the Nordic Prize for Alternatives to Animal Experiments 2014, awarded at the Digital Health Days conference, held in late August in Stockholm, to Christel Bergström, Maria Karlgren and Pär Matsson at Uppsala University for their contribution of animal-free methods in drug development. The team has used cell models and computer models to study intestinal drug transport, side effects and drug interactions. Using these screening and predictive methods prior to preclinical testing will aid drug design and identify benefits and risks early on, thus reducing animal testing.