Gyrolab Spin Blog

Oct 27, 2015 9:14:00 AM

High throughput screening in biologics process development with a minimum of material

Matching scale-down high throughput screening with efficient analytical methods makes the most of precious material

Combining high throughput and small-scale purification methods is a key strategy in bioprocess development. John Welsh and his colleagues at Merck & Co. Inc, USA could develop three orthogonal purification steps using less than 200 mg of a domain antibody fragment, orders of magnitude less than what would typically be required for process development. 

 

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Topics: Bioprocess, HCP