Gyrolab Spin Blog

Dec 15, 2015 3:57:00 PM

How to boost clone screening in recombinant therapeutic protein development

bottle_cloned.pngHigh-throughput immunoassays underpin efficiency and productivity

Automation is being applied at many levels to power future development of recombinant therapeutic proteins, including screening for the most promising recombinant protein clones. Gregory Keil and co-authors at Merck & Co. have reviewed how this screening can be transformed by combining high-throughput screening methods, analytical techniques and automation to increase capacity, reduce manual operations and risk for error, lower operational costs, and shorten development timelines (see reference).

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Topics: Assay Automation, Bioprocess


Feb 10, 2015 3:28:00 PM

Latest news from SLAS 2015: Gyrolab xPlore brings new agility to immunoassays

Accelerate every phase of your biopharma development

With the SLAS tagline ‘Come Transform Research’, we feel very much at home at this year’s Annual Conference and Exhibition, especially since we have come to launch a brand new system – Gyrolab xPlore, a smaller companion to Gyrolab xP workstation!

slas2015-2

 

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Topics: Assay Automation, Biomarkers, Pharmacokinetics, Serial sampling, Microsampling


Jul 22, 2014 6:18:00 AM

Working in Harmony with Multiple Ligand-Binding Assay Platforms

Guidelines for automating your LBAs for GxP

Harmony3Thinking about automating ligand-binding assays (LBA) for a GxP environment? Assay automation can bring great value, including time and cost savings, better results, higher throughput, lower sample volume requirements and simplified proof-of-concept than manual methods. But each platform is different and brings its own protocols, recommendations and constraints. How does one even begin to define parameters that might be critical in validating assays on different types of platforms?

 

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Topics: Assay Automation


Apr 30, 2014 5:30:00 PM

Webinar Summary: Automating Pharmacokinetic Bioanalysis

Automating Pharmacokinetic Bioanalysis at Nanoliter-Scale: Strategies for Development, Validation and Transfer

[WEBINAR RECAP]

If you missed the webinar from Cambridge Healthtech Institute on March 18, 2014, don’t worry. We’ve provided a summary here about how two research groups developed robust high performance nanoliter scale assays on the Gyrolab platform, as well as a link to the full webinar.

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Topics: Assay Automation


Apr 2, 2014 6:15:00 PM

Three ways your pre-clinical toxicology team can do more with less

Using microfluidics platform to measure toxicology biomarkers with less sample

Do more with less. It’s an age-old concept, but this mantra especially resonates in today’s pre-clinical toxicology world as the pharmaceutical industry faces greater than ever challenges in getting lead compounds to market.

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Topics: Assay Automation, Toxicology assays